In the realm of biomedical research, few discoveries have been as transformative as Gary Ruvkun's microRNA discovery in the early 1990s, a groundbreaking achievement that ultimately led to him receiving the 2024 Nobel Prize in Physiology or Medicine.Collaborating with Victor Ambros, Ruvkun unearthed the vital role that microRNAs play in gene regulation, uncovering insights that extend to a myriad of organisms, including humans.